Evaluation of serum ARGS neoepitope as an osteoarthritis biomarker using a standardized model for exercise-induced cartilage extra cellular matrix turnover
نویسندگان
چکیده
منابع مشابه
Extra-cellular Lipid in the Matrix of Human Articular Cartilage.
The presence of fat and other lipids within the cytoplasm of cartilage cells has often been observed. Collins, Ghadially, and Meachim (1965) in a previous paper have described this phenomenon in some detail. They find that intra-cellular lipid is an almost constant feature of the chondrocytes of adult hyaline cartilage in various anatomical situations in man and rodents, that it is more promine...
متن کاملCartilage oligomeric matrix protein neoepitope in the synovial fluid of horses with acute lameness: A new biomarker for the early stages of osteoarthritis
BACKGROUND Clinical tools to diagnose the early changes of osteoarthritis (OA) that occur in the articular cartilage are lacking. OBJECTIVES We sought to identify and quantify a novel cartilage oligomeric matrix protein (COMP) neoepitope in the synovial fluid from the joints of healthy horses and those with different stages of OA. STUDY DESIGN In vitro quantitative proteomics and assay deve...
متن کاملFK506 protects against articular cartilage collagenous extra-cellular matrix degradation.
OBJECTIVE Osteoarthritis (OA) is a non-rheumatologic joint disease characterized by progressive degeneration of the cartilage extra-cellular matrix (ECM), enhanced subchondral bone remodeling, activation of synovial macrophages and osteophyte growth. Inhibition of calcineurin (Cn) activity through tacrolimus (FK506) in in vitro monolayer chondrocytes exerts positive effects on ECM marker expres...
متن کاملthe use of appropriate madm model for ranking the vendors of mci equipments using fuzzy approach
abstract nowadays, the science of decision making has been paid to more attention due to the complexity of the problems of suppliers selection. as known, one of the efficient tools in economic and human resources development is the extension of communication networks in developing countries. so, the proper selection of suppliers of tc equipments is of concern very much. in this study, a ...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage Open
سال: 2020
ISSN: 2665-9131
DOI: 10.1016/j.ocarto.2020.100060